This is a MS batch file, good for Windows 98-XP.

Just copy this into a text file called 'copy.bat' and edit the directories.
The first directory is the original, the second is the copy destination.  If
you need an e drive copied to a USB drive, it could be as simple as
"xcopy /E /I /F /H /R /K /Y /D e:\ u:\ >> u:\backuplog.txt".  In this script,
we copy directories on the [s]ource drive to the [d]estination drive.  This
could be USB, CDRW, or another HD.

REM Writes a timestamp
echo START > "d:\LAST NIGHTLY BACKUP.txt"
date /t >> "d:\LAST NIGHTLY BACKUP.txt"
time /t >> "d:\LAST NIGHTLY BACKUP.txt"

xcopy /E /I /F /H /R /K /Y /D "s:\Documents and Settings\Administrator\My Documents" "d:\My Documents" >> "d:\LAST NIGHTLY BACKUP.txt"

xcopy /E /I /F /H /R /K /Y /D "s:\My Pictures" "d:\pictures" >> "d:\LAST NIGHTLY BACKUP.txt"

xcopy /E /I /F /H /R /K /Y /D "s:\Documents and Settings\Administrator\Favorites" "d:\Favorites" >> "d:\LAST NIGHTLY BACKUP.txt"

xcopy /E /I /F /H /R /K /Y /D "s:\Program Files\Quicken" "d:\quicken" >> "d:\LAST NIGHTLY BACKUP.txt"

REM Updates timestamp
echo STOP >> "d:\LAST NIGHTLY BACKUP.txt"
date /t >> "d:\LAST NIGHTLY BACKUP.txt"
time /t >> "d:\LAST NIGHTLY BACKUP.txt"